Perioperative myocardial protection
نویسنده
چکیده
Myocardial protection refers to all strategies that increase the heart’s ability to withstand ischaemic insult, which together with reperfusion injury are principally responsible for cardiac morbidity and mortality after high-risk surgery. The bloodless and motionless operating conditions required for cardiac surgery is an environment diametrically opposed to the metabolic demands of the heart.
منابع مشابه
Antiplatelet therapy for carotid artery stenting.
Carotid artery stenting (CAS) is less invasive and has a lower incidence of systemic complications such as myocardial infarction compared with carotid endarterectomy. However, CAS is known to have a high incidence of ischemic complications due to distal thromboembolism. Progress has been made in the development of various distal protection devices and protection methods aimed at preventing thro...
متن کاملAlpha2-adrenergic agonists and their role in the prevention of perioperative adverse cardiac events.
Alpha2-adrenergic agonists have been shown to reduce the incidence of perioperative myocardial morbidity and mortality. The purpose of this review article is to summarize the current data pertaining to alpha2-adrenergic agonists and their role in the prevention of perioperative adverse cardiac events. The MEDLINE and Cochrane databases were searched for randomized trials from 1980 to 2006 that ...
متن کاملPhysiology and pharmacology of myocardial preconditioning.
Perioperative myocardial ischemia and infarction are not only major sources of morbidity and mortality in patients undergoing surgery but also important causes of prolonged hospital stay and resource utilization. Ischemic and pharmacological preconditioning and postconditioning have been known for more than two decades to provide protection against myocardial ischemia and reperfusion and limit ...
متن کاملLetter by Naggara et al regarding article, "Are distal protection devices 'protective' during carotid angioplasty and stenting?".
BACKGROUND AND PURPOSE To evaluate the periprocedural outcome after carotid artery stenting with embolic brain protection (EBP+) versus without embolic brain protection (EBP-). METHODS We retrospectively reviewed data from a prospective nonrandomized database of 357 patients who underwent carotid artery stenting in the neuroradiology division of our institution from 1999 to 2009. One hundred ...
متن کاملPii: S1010-7940(01)00709-6
Objectives: Heart-type fatty acid binding protein (hFABP) is an intracellular molecule engaged in the transport of fatty acids through myocardial cytoplasm and has been used as a rapid marker of myocardial infarction. However, its value in the evaluation of perioperative myocardial injury has not yet been assessed. Methods: 32 consecutive patients undergoing coronary artery bypass grafting were...
متن کامل